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Winnie may be acting this way because of a smell. Does your nephew smoke? Does he secretly smoke? Is there another smell on him that she is reacting to? Is he on any medication? Is he diabetic (high insulin level)

Also, at this age schizophrenia can be beginning. People with schizophrenia have an off putting smell, at least when their boy is rolling into an episode. This would be very unlikely, but some dogs react to the smell.
 
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