After the first year booster, I follow the law on the rabies and I might revaccinate everything at three years (or I might not depending on what the risk factors are for the particular dog and my lifestyle at the time). After that we are done. Bordatella as needed. If showing a dog I used to get the bordatella once a year. Heartworm monthly. Flea meds only needed if you live somewhere there are fleas. Different stuff works different ways depending on the local fleas.