I spent the better half of 20 years in Durham, NC, and yet I never had a tick (or chigger) on me until I got Mia, who attracted ticks year round. If you do a search here for related threads, a lot of people have looked for a natural spray. Unfortunately, IME, they simply don't work as well or as long as DEET (on the human) and an oral tablet (e.g. Bravecto, for the dog).
For the dog, Mia is old enough that topicals were still prevalent when she was young. The dogs hated them, I hated them, and they didn't last the whole month between swimming and hiking. I regularly found ticks, dead and alive, on Mia, and some were engorged. I would pick 20-30 off of her after a hike, and still miss a few. She now tests positive for exposure to several tick-borne illnesses (without checking her records, I think they are RMSF, ehrlichia, lyme).
About 7-8 years ago oral tablets became available. There was a lot of hub-bub about safety, but they've proven themselves to be safe and effective. Mia is on Bravecto, and while I still find a tick or two on her from time to time, they're dead.
For people, there's simply nothing better than DEET if you're heading into the woods. It's safest to use a 5% spray and reapply often rather than use a higher percentage and reapply less frequently.
If you're stuck on wanting to use something natural, don't go into the woods. I found natural oils might keep me tick free while walking through my neighborhood, where I was unlikely to pick a tick in the first place, but that's about it. I had better luck with a tomato-based spray in development at NC State, but it wasn't something I would take to the woods -- maybe a friend's wooded backyard. These sprays didn't work on the dogs, either, and it didn't help that the sprays probably brushed off in the tall grass or washed off crossing creeks.
For the yard, try diatomaceous earth. DE is awesome. Make sure to wear a mask when applying, because the particles are small and will get into your lungs. I tried applying to the dogs, but it dried out their skin, so I stuck to using it around the yard/garden.
Final thought: chickens eat ticks. I haven't had a backyard coop, but this alone makes it tempting.