We use the medications. Also when in an area we check at least once daily for ticks. We have a "tick removal tool", which we take with us all the time. We had a tick on the skin (not embedded) that I found about a month ago. (only been around our home). We just got back from traveling--and found one tick on Gigi on the trip. We check at least 2x a day, and especially before bedtime for ticks.