I think my parents' last dog was driven partway from/by the breeder and stay in a motel one night before being picked up by my folks who drove the dog the rest of the way home. I'd do it I think, but one night in a hotel would be my limit. It just feels so important to get to a home base where you can start your routines. Dealing with a tiny non-housetrained puppy on someone else's carpets would stress me out even if it didn't make too much of a difference for the dog.