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There is an interesting summary of research and meta-analysis of studies into the risks and benefits of vitamin and other supplements here: Evidence Concerning Vitamin and Mineral Supplements- Safety and Efficacy | The SkeptVet Blog

It is all human research, but the general message is that unless there is a medically established deficiency, supplements are at best a waste of money, and at worst positively harmful. A decent diet is the best protection...
 

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Skepvet has a grudge against natural and alternative treatments. He fully supports the medical establishment which is influenced by the pharmaceutical industry who refuse to publicly acknowledge that natural substances can heal.

Unlike drugs, natural supplements cannot be patented so big pharma constantly puts "research" out there in an attempt to discredit their use. We're used to that. ;)

Dr. Shawn’s Blog » Why SkeptVet Might Be Skeptical
 

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Looking at the studies covered, most were actively looking for benefits - these are main stream, high volume supplements making their producers and distributors very large sums of money, after all. I don't think Skeptvet has a grudge exactly - more a disinclination to trust claims that have not been fully tested. I think we could gain a lot from applying thorough scientific testing to many of the things that have become received wisdom over the years - the need for annual vaccination was one of the first to go when thoroughly examined, for example.
 
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