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Old 01-30-2016, 10:43 AM   #1 (permalink)
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Default Public Health Issues Discussed at the Vet Yesterday

1. They have seen breakthroughs on not just topical flea and tick controllers but also some of the new ones like the seresto collar. While I have always given Lily and Peeves a winter holiday from flea/tick/heartworm control we are switching to year round protection.

2. Heartworms have started to show resistance to ivermectin.

3. There was a sign on the front door of the clinic telling people that there has been rampant Bordatella in our area recently. Clients were directed not to bring any dog that was coughing or showing other respiratory signs into the building. When Lily had it the doctor came out and examined her in the back seat of my truck rather than allowing her in the building. They are strongly recommending immunizing all dogs that have public life contact with other dogs they may not know. I know many of you disagree with giving this vaccine, but I am just reporting the opinions of the professionals at the clinic I go to (so don't beat me up on this one).

4. There is a new strain of flu circulating widely in dogs in the US. It is H3N2, different virus type than last year.

5. We have never given Lily or Peeves the Lyme vaccine but this doctor (not our usual) suggested considering it since I did say that I have seen ticks on the dogs occasionally (dead ones, so at least our Advantix is still working) and since I told her I had been bitten by a tick that I picked up at an agility trial last spring.
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Old 01-30-2016, 11:36 AM   #2 (permalink)
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Isn't that the only type of heartworm prevention (well actually heartworm killer because it does not prevent them it just kills them in the early stage) that there is? Huge problem if it stops being effective!
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Old 01-30-2016, 01:55 PM   #3 (permalink)
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Milbemycim oxime is the heartworm preventative in sentinel, which we use. I just looked it up and read that it is less effective than ivermectin.
Theo just had a terrible reaction to frontline, after using it for 4 years or so. Sentinel isn't enough for fleas for him in the summer and I'm deciding what to do.
I am going to get them vaccinated with the new vaccine for the new strain of flu, at their annual. Did you get them vaccinated lily cd?
I do get mine vaccinated for Lyme because my vets have explained in detail how the new vaccine doesn't trigger as severe an autoimmune response as the older one. I'm interested to know if your vet talked about this at all?
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Old 01-30-2016, 02:40 PM   #4 (permalink)
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Have you thought of Nexgard for fleas and ticks? Then you could give the heartworm med separately.
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Old 01-30-2016, 03:21 PM   #5 (permalink)
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As far as killing fleas and ticks, Ari's groomer (D. Conner for those that care) says that NexGard and Bravecto work best; of the two, she thinks Bravecto is slightly more effective on deer ticks in Maine. She sees dozens of dogs every week and when she finds ticks on them she makes note of what flea/tick prevention they are on. She finds ticks incredibly efficiently because of the big dryer she uses.

When dogs come in on Bravecto, she told me that the ticks she find are always dead and turn into powder when she combs them out (gross I know) whereas on NexGard they are dead but still "whole" and with Frontline/other topicals, they are sometimes alive and wiggling although usually not engorged. She can now predict what medication a dog is taking based on the state of the ticks she picks off of them.

Ari will get the Lyme vaccine this spring/summer because it is so rampant in our area and because even with the tick meds, the ticks are able to attach and that carries some risk of infection. I'm glad I elected to wait on the Lyme vacc because I would totally have blamed her seizures on a bad vaccine reaction had I let them give it to her at 6 months old!!!
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Old 01-30-2016, 04:21 PM   #6 (permalink)
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Theo's mom, since Lily and Peeves got rabies 3 year plus Bordatella yesterday we didn't do any other immunizations (including flu) at this visit, but I plan to do some more research and really think about my planning for where I will show (especially for agility) as part of our decision making on the Lyme vacc. I am very concerned about the potential for ivermectin (Iverhart) resistance regarding the heart worm issues. This resitance is one of the most concerning of these issues to me since ivermectin has been such a great gold standard for round worms for such a long time. At this point we will retest Lily and Peeves for heart worms in March and then put them on continuous preventive treatment. Javelin has had continuous Iverhart.

sophie anne bravecto is systemic/oral, right? Saresto wasn't going to work for us since Lily and Peeves have a history of taking collars off each other. Also there can only be one collar on a dog in an AKC event.
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Old 01-30-2016, 05:36 PM   #7 (permalink)
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Quote:
Originally Posted by lily cd re View Post
sophie anne bravecto is systemic/oral, right? Saresto wasn't going to work for us since Lily and Peeves have a history of taking collars off each other. Also there can only be one collar on a dog in an AKC event.
Both Bravecto and NexGard are systemic/oral.

NexGard website.
Bravecto website.

More about the active ingredients in NexGard/Bravecto

Ari was on NexGard for the summer, but I may try Bravecto this spring. Both have an association with seizures in dogs with epilepsy (but haven't been, to my knowledge, shown to be causative) so I am apprehensive about starting her back up on it. At this point, I do not think Ari has epilepsy, but that episode was so scary and I would tear myself up if I thought giving her something caused more seizures... She swims too much for anything topical to be a reasonable alternative. Fortunately, I have a couple months to agonize over this before spring.

This is a quote from Dr. Dodd's email to me back in the midst of the craziness of her seizures:
Quote:
Also, no spinosad (Comfortis; Tri-Fexis) or afoxolaner (NexGard) or fluralaner (Bravecto) for flea control, and for ticks. Indoxacarb (Activyl or Activyl Plus) are acceptable.
Here is the pamphlet that discusses NexGard and seizures:
Prescribing Information Pamphlet
Quote:
In a well-controlled US field study, which included a total of 333 households and 615
treated dogs (415 administered afoxolaner; 200 administered active control), no serious
adverse reactions were observed with NexGard.
In the US field study, one dog with a history of seizures experienced a seizure on the
same day after receiving the first dose and on the same day after receiving the second
dose of NexGard. This dog experienced a third seizure one week after receiving the
third dose. The dog remained enrolled and completed the study. Another dog with
a history of seizures had a seizure 19 days after the third dose of NexGard. The dog
remained enrolled and completed the study. A third dog with a history of seizures
received NexGard and experienced no seizures throughout the study.
Bravecto Prescribing info:
Prescribing info pamphlet Bravecto
Quote:
There were no clinically-relevant, treatment-related effects on the body weights, food
consumption, reproductive performance, semen analysis, litter data, gross necropsy
(adult dogs) or histopathology findings (adult dogs and puppies). One adult treated
dog suffered a seizure during the course of the study (46 days after the second
treatment). Abnormal salivation was observed on 17 occasions: in six treated dogs
(11 occasions) after dosing and four control dogs (6 occasions).
I did a biochem research internship at the lab that collected the sponge that inspired the compound for NexGard/Bravecto, which I think is pretty neat!
Marine sponge metabolites
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Old 01-31-2016, 02:57 AM   #8 (permalink)
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sophie anne thanks so much for posting all that documentation. This really is a public health problem for which many of us will have to be doing research and making decisions on in the next months and years. The main part of why I started this thread was so that we could all talk about the options we have chosen or are considering and get feedback from each other to help us make the best care decisions we can for our dogs.
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Old 01-31-2016, 07:04 AM   #9 (permalink)
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We don't need heartworm preventative up here, thank goodness; it hasn't made its way up this far yet. We also don't have a problem with ticks or fleas...they get frozen out in the winter i guess. But we DO have a problem with rabies because it does occur in coyotes, bobcats and foxes which run all over my property. So you better believe I am right up to date on my rabies protocol with all our dogs, and also all regular vaccines and bordatella. Obedience lessons, groomers and boarding kennels won't take your dog if they're not up to date on vaccines and bordatella and since I occasionally make use of all of the above, everyone is utd on all. I've never had a problem with reactions, thank goodness.
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Old 01-31-2016, 08:20 AM   #10 (permalink)
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In regard to Bravecto vs Nexgard, my gut reaction is that something that lasts in their system 3 months has got to be "stronger or more toxic" than something that lasts a month. Timi has done fine on Nexgard, and we certainly are not in a high risk area - her biggest risks might be catching them from other dogs at dog parks, or maybe Central Park, but I am wondering if you ladies who understand the science behind the two could comment on which you feel might be "safer"?
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